Does CBD Topical Cream Show Up on Drug Tests?
Written by: Daniel Fayad, Subject Matter Expert and Website President
Published: March 15, 2024; Last updated: April 6, 2024
- 1. Key Takeaways
- 2. CBD Topicals: What Are They?
- 2.1 Types of CBD Topicals
- 2.2 How CBD Topicals Work
- 3. THC vs CBD: Understanding the Difference
- 3.1 Legal Status of CBD
- 4. Drug Tests: What Do They Look For?
- 4.1 Types of Drug Tests
- 4.2 Detection Windows
- 5. Can CBD Topical Cream Show Up on a Drug Screen?
- 5.1 Absorption Through the Skin
- 5.2 Choosing the Right CBD Topical
- 6. Factors That May Affect CBD Topicals and Drug Test Results
- 6.1 Product Quality and Labeling Accuracy
- 6.2 Cross-Contamination and Mislabeling
- 7. Tips for Using CBD Topicals Safely With Drug Tests
- 7.1 Opt for Broad-Spectrum CBD or CBD Isolate Products
- 7.2 Start with Low Doses
- 7.3 Communicate with Employers
- 8. Summary
- 9. Frequently Asked Questions
- 9.1 Does topical CBD show up in urine?
- 9.2 How long does topical CBD cream stay in your system?
- 9.3 What does CBD do in topical cream?
- 9.4 What factors can affect the likelihood of a positive drug test result when using CBD topicals?
- 9.5 What precautions can I take to ensure that I’m using CBD topicals safely with drug tests?
- 10. References
Imagine this: You’re an active individual who frequently uses CBD topicals for muscle soreness. You’ve been enjoying the targeted relief it provides, but suddenly, you’re required to take a drug test at work. You’re left wondering, does CBD topical cream show up on drug screens? This question is more common than you might think, and in this blog post, we’ll delve into the details and provide some clarity.
Key Takeaways
CBD topicals such as creams, lotions, and balms interact with the skin’s endocannabinoid system for localized relief without entering the bloodstream. Therefore, they are unlikely to result in a positive drug test for THC.
Legally, hemp-derived CBD products must contain less than 0.3% THC; however, product quality and accurate labeling are critical to avoid inadvertently consuming higher THC levels, which might cause a positive drug test.
To minimize drug testing risks, individuals should opt for broad-spectrum or CBD isolate products, start with low doses of CBD topicals, and maintain transparent communication with employers regarding CBD use.
CBD Topicals: What Are They?

You might have encountered CBD topicals, but what do they entail? CBD topicals, also known as topical CBD products, are infused with cannabidiol extracts sold online or in stores and are applied directly to the skin for localized relief. They’re available in various forms, such as creams, lotions, and balms, and are commonly used for many wellness benefits.
CBD topicals are produced by:
Heat petrolatum and blend Sepigel with water until a uniform slurry is achieved.
Introducing the liquefied petrolatum with agitation.
Adding CBD along with other preservatives.
CBDfx, a famous brand in the CBD industry, utilizes full spectrum CBD, broad spectrum CBD oil, or CBD isolate in their CBD hemp topicals.
The key ingredient in these topical products is CBD, a cannabis compound found in hemp plants. Unlike THC (tetrahydrocannabinol), which is another well-known cannabinoid, CBD is non-intoxicating and offers potential wellness benefits without the characteristic high associated with marijuana use.
Types of CBD Topicals
The CBD industry has grown exponentially over the past few years, making many CBD topicals available. These include:
lotions
creams
salves
balms
gels
All with distinct formulations and potential benefits.
CBD creams, such as CBD lotion, are typically formulated to:
Reduce inflammation
Offer soothing relief
Alleviate discomfort associated with conditions such as arthritis
Address skin concerns like eczema and psoriasis
Moisturize dry skin
Promote physical comfort
Rejuvenate sun-affected skin
Support clear skin
Induce relaxation
On the other hand, CBD lotions generally contain a higher water content, enabling easier absorption by the skin. They are similar to creams but have a less dense consistency.
CBD balms and salves are recognized for promoting relaxation, delivering specific relief, and possessing anti-inflammatory properties. They are advantageous for alleviating muscle discomfort post-exercise and minimizing inflammation.
How CBD Topicals Work
How do these CBD topicals function? The answer lies in our skin’s endocannabinoid system. When CBD topicals come into contact with the skin, they interact with this system, offering targeted relief without entering the bloodstream.
The endocannabinoid system in the skin influences allergic inflammation, skin barrier functions, inflammatory responses, and wound healing. It may also affect skin conditions such as atopic dermatitis and melanoma. CBD topicals work by inhibiting pain and itch sensations through CB1 receptors, modulating immune functions, and potentially providing therapeutic effects for inflammatory skin diseases. ¹
This is crucial because it implies that CBD topicals, unlike other CBD products, are unlikely to cause you to fail a drug test. Since these products are specifically formulated not to enter the bloodstream, they don’t pose the risk of a positive drug test result.
THC vs CBD: Understanding the Difference
Distinguishing between THC and CBD can help comprehend why CBD topicals are less likely to yield a positive drug test. THC, or tetrahydrocannabinol, is the psychoactive compound in cannabis that induces a ‘high.’ On the other hand, CBD, or cannabidiol, is non-intoxicating and does not produce a high. This highlights a significant contrast in their impact on the mind.
Despite sharing the same chemical structure, THC and CBD have distinct psychoactive effects and medicinal properties.
THC can induce adverse effects, including:
Nausea
Diarrhea
Gastrointestinal discomfort
Fatigue
Dizziness
Irritability
Hypotension
However, CBD does not possess the psychoactive characteristics of THC and is typically well-tolerated and devoid of the euphoric effects commonly attributed to THC.
Both THC and CBD offer medicinal benefits, including:
Anxiety relief
Chronic pain treatment
Regulation of mood and immune responses
Potential assistance in lowering blood pressure
However, the potential for THC to show up on a drug test makes it a matter of concern for many CBD users, particularly those who might be subjected to drug testing.
Legal Status of CBD
CBD’s legal status is a complex issue due to the variety of laws at the federal and state level. The 2018 Farm Bill legalized some hemp-derived CBD products with less than 0.3% THC at the national level, excluding hemp from the legal definition of marijuana in the Controlled Substances Act. However, hemp products are still required to comply with FDA regulations.
The 0.3% THC limit is crucial as per federal law, which stipulates that hemp cannot contain more than 0.3% THC. Products exceeding this limit are categorized as marijuana and are prohibited at the national level. However, individual states have their regulations about CBD. Certain states have fully legalized CBD for medical or recreational purposes, while others may consider all cannabis products to be illegal.
Non-compliance with CBD regulations at the federal level may result in significant penalties, including:
Imprisonment for 5-40 years
Fines ranging from $2-$5 million for quantities less than 1000 kilograms or plants
Ten years to life imprisonment plus $4-$10 million in fines for quantities of 1000 kilograms or more
State penalties can exhibit considerable variation. Therefore, it’s essential to understand and adhere to all CBD regulations to avoid potential legal consequences.
Drug Tests: What Do They Look For?
Having covered the fundamentals of CBD topicals, our discussion will now pivot to drug tests. Drug tests commonly screen for THC and its metabolites to detect marijuana use. However, routine drug tests do not usually screen for CBD because it is not considered an illicit ingredient, unlike THC.
Interestingly, even though drug tests do not specifically screen for CBD, CBD users still can test positive for THC. This is because some CBD products may contain trace amounts of THC that can accumulate in the body over time. However, as discussed earlier, CBD topicals are less likely to result in a positive drug test due to their minimal absorption through the skin. With this in mind, it’s essential to consider a CBD drug test when using these products.
It’s also worth noting that drug tests are not flawless. There have been instances of false positives, where individuals who have not used any THC products have tested positive for THC. This can occur due to cross-reactivity, where the drug test reacts to a substance that is similar in structure to THC, leading to a false positive result.
Types of Drug Tests
There are several types of drug tests, each with different detection windows and sensitivity. The most commonly used drug tests include urine, hair, blood, and saliva tests. ³
Urine drug tests are the most prevalent form of drug screening. They function by utilizing a biological specimen, such as urine, to identify the presence or absence of lawful or unlawful drugs. Hair tests, on the other hand, can detect substances over up to 90 days and, in some instances, up to 12 months.
The type of test used can significantly impact the detection window for THC. For instance, cannabinoids may be detectable in urine for up to six weeks in the case of heavy CBD or THC users. THC can be detected in a single hair follicle for approximately 90 days at a detectable level, unlike other substances, which may have a shorter noticeable window.
Detection Windows
The detection window for THC in drug tests can vary greatly depending on a range of factors. These include the type of test used and individual variables, such as the frequency of drug use and the individual’s metabolism.
For instance, cannabinoids may be detectable in urine for up to six weeks in the case of heavy CBD or THC users. However, the detection window can be much longer for hair drug tests, with THC potentially detectable in a single hair follicle for approximately 90 days at a detectable level.
It’s crucial to remember that these detection windows are estimates and can vary greatly depending on the individual’s metabolism, frequency of use, and even the potency and dosage of the CBD product used.
That’s why it’s always a good idea to take precautions if you’re subjected to drug testing, even though the risk of a positive result from using CBD topicals is relatively low.
Can CBD Topical Cream Show Up on a Drug Screen?
Considering our discussion thus far, a question might arise: Can CBD topical cream be detected in a drug screen? The answer, in short, is it’s doubtful. CBD topicals provide relief by interacting with the skin’s endocannabinoid system, offering targeted relief without entering the bloodstream.
It’s important to note that the probability of testing positive for marijuana or THC after using CBD topicals is relatively low. That’s because the skin serves as a formidable barrier, effectively hindering substantial penetration of THC and its entry into the bloodstream when CBD topicals are used. ²
However, factors such as a positive drug test result could still lead to a failed drug test. These include the use of poorly regulated or low-quality products that may contain higher levels of THC than stated on the label, as well as cross-contamination of CBD products with THC during the manufacturing process.
Absorption Through the Skin

Let’s explore the role of skin as a barrier to THC absorption. When CBD topicals are applied to the skin, the CBD is absorbed and enters the sebaceous gland via the hair follicles. It also can attach to cannabinoid receptors located in the skin.
This interaction is localized, meaning CBD topicals relieve the specific area where they’re applied without entering the bloodstream. This is a crucial point because substances that enter the bloodstream have the potential to be detected by drug tests.
That said, the skin’s lipid barrier significantly influences the absorption of CBD and THC. Although CBD may have some ability to penetrate the skin, the integrity of the barrier, particularly with low levels of linoleic acid, affects the permeability to substances such as CBD and THC.
Choosing the Right CBD Topical

Selecting an appropriate CBD topical is vital to prevent problems with drug tests. This involves looking at the type of CBD used (broad-spectrum or CBD isolate) and verifying the product’s quality and accuracy of labeling.
Around 60% of CBD products sold in the United States have been found to have inaccurate labeling, failing to align with the advertised CBD content. Therefore, it’s crucial to choose products that have undergone third-party lab testing to ensure the quality and accuracy of labeling.
The label of a CBD topical should include the following details:
Product’s identity
Components
Brand denomination
Adherence to overarching regulations specific to the product category (such as food, supplement, or cosmetic)
Brand name
Physical address
Contact details
Comprehensive list of ingredients and potential allergens
Factors That May Affect CBD Topicals and Drug Test Results
Besides the type of CBD topical used, other elements can influence the probability of a positive drug test result. These include the product’s quality, labeling accuracy, and cross-contamination.
Inaccurate or misleading product labeling can lead to the use of CBD topicals that contain higher levels of THC than stated on the label. This can result in a positive drug test result for THC, a psychoactive compound found in cannabis.
Cross-contamination is another potential issue. This can occur during CBD products’ cultivation, processing, or packaging. This risk is heightened when CBD products are produced in facilities that also handle THC products, leading to the potential transfer of THC to the CBD product.
Product Quality and Labeling Accuracy
The quality of the CBD topical and the accuracy of its labeling are crucial factors when it comes to avoiding potential THC exposure. Approximately 60% of CBD products in the United States have been found to have inaccurate labeling, so it’s essential to choose products that have undergone third-party lab testing to ensure their quality and accuracy of labeling.
When examining a CBD topical label, it’s essential to verify that the product’s measured total amount of CBD falls within 10% of the labeled total amount. Additionally, proving that the CBD and THC concentrations on the Certificate of Analysis (COA) align with the information stated on the label is crucial.
It’s worth noting that the label of a CBD topical should encompass packaging options like:
Child-resistant containers
A comprehensive list of ingredients encompassing carrier oils
A suitable disclaimer
Preferably, glass packaging to ensure its quality and safety.
Cross-Contamination and Mislabeling
Cross-contamination during the manufacturing or storage of CBD products can result in trace amounts of THC being present in the products. This can occur during cultivation, processing, or packaging, mainly when CBD products are produced in facilities that also handle THC products.
The presence of moisture can result in contamination and the proliferation of harmful microorganisms when CBD products are exposed. Furthermore, the handling of CBD products by workers can also contribute to cross-contamination, which is a notable concern given the bioaccumulative properties of cannabis products.
Measures such as appropriate storage, temperature controls, and procedures are implemented to prevent cross-contamination in the CBD manufacturing process. Additionally, methods such as establishing vegetative buffers, conducting thorough employee training, employing disinfectant mats, and utilizing food-grade chemicals for cleaning and sanitizing are implemented.
Tips for Using CBD Topicals Safely With Drug Tests
For CBD topical users anxious about drug tests, rest assured there is little cause for concern. It’s doubtful that CBD topicals would cause you to test positive for THC. However, there are still some precautions you can take to ensure that you’re using CBD topicals safely with drug tests.
One of the most secure forms of CBD products to use when there is a concern about drug testing is broad-spectrum CBD and CBD isolate. Broad-spectrum products contain a variety of cannabinoids except THC, while CBD isolate consists purely of CBD without any additional compounds from the cannabis plant.
Another tip is to start with low doses of CBD topicals. While employing small amounts of CBD topicals can reduce the possibility of THC exposure, consistent usage of low doses or utilization of products containing THC due to inaccurate labeling may elevate the risk of testing positive on a drug test.
Opt for Broad-Spectrum CBD or CBD Isolate Products

If you’re concerned about drug testing, opting for broad-spectrum or CBD isolate products can be a safe choice. Broad-spectrum CBD contains additional compounds found in the cannabis plant while having all THC removed. This makes it a viable option for individuals who have apprehensions about drug testing, as no THC present could potentially trigger a positive result on a drug screen.
CBD isolate, on the other hand, is produced through the extraction of CBD from the hemp or cannabis plant, followed by a refining process to eliminate all other compounds. This yields a product that is 99% pure CBD and devoid of THC, rendering it an exceptionally safe option for users who are mindful of drug testing concerns.
While both broad-spectrum and CBD isolate products lack THC, they can still offer the potential wellness benefits associated with CBD. Broad-spectrum CBD provides various beneficial compounds without THC, while CBD isolate offers pure CBD. This reduces the likelihood of a positive drug test outcome, making these products a sensible choice for those subjected to drug tests.
Start with Low Doses
Starting with low doses of CBD topicals can also help minimize potential THC exposure. The suggested initial dosage for CBD topicals is approximately 5 mg to 10 mg two to three times a day. As you become more accustomed to the effects of CBD, you can gradually increase your dosage to find the optimal amount that delivers the desired effect while minimizing undesirable reactions.
It’s crucial to monitor your reactions to CBD topicals, as specific individuals may encounter adverse effects such as diarrhea or liver problems. Additionally, it’s essential to remain vigilant for potential drug interactions, especially if you’re concurrently using other medications.
It’s always a good idea to consult a healthcare professional before starting any new wellness regimen, including CBD topicals. They can guide appropriate dosages and potential interactions with other medications you’re taking.
Communicate with Employers
One more crucial step for the safe use of CBD topicals when facing drug tests is engaging in open communication with your employer. If your job entails drug testing, it’s advisable to inform your employer about your CBD use. Transparent communication can assist in establishing clear expectations and addressing any potential concerns that may stem from your CBD use.
When informing your employer about your use of CBD topicals, it’s advisable to approach the matter transparently and professionally. Here are some steps to follow:
Initiate a conversation with your HR representative or direct supervisor.
Consider providing educational resources about CBD and, if applicable, a recommendation from your doctor.
Be forthright about the THC content in your CBD product, as this information could be relevant to company policies and drug testing.
Summary
In summary, while CBD topicals are unlikely to result in a positive drug test, it’s crucial to use them responsibly, especially if you’re subjected to drug testing. Choose high-quality products that have undergone third-party lab testing, opt for broad-spectrum or CBD isolate products to avoid THC, and start with low doses. Remember to communicate openly with your employer about your CBD use to avoid any misunderstandings.
It’s all about being informed and making intelligent decisions about your health and well-being. Whether you’re an athlete looking for relief from muscle soreness or an individual seeking natural wellness alternatives, CBD topicals can be a beneficial addition to your routine. Just remember to use them responsibly and stay informed about the potential implications of drug testing.
Frequently Asked Questions
Does topical CBD show up in urine?
No, topical CBD products do not show up in urine because the skin effectively protects against penetration into the bloodstream. Therefore, they alone will not result in a positive drug test.
How long does topical CBD cream stay in your system?
Topical CBD cream can stay in your system for about 2-5 days, with the likelihood of traces remaining for up to 3.5 days. The duration depends on regularity and dosage of use.
What does CBD do in topical cream?
Topical CBD cream can reduce intense pain, itching, and inflammation, making it beneficial for joint and muscle pain and certain skin disorders. Additionally, it has been found to have anti-inflammatory, analgesic, and wound-healing effects on the skin.
What factors can affect the likelihood of a positive drug test result when using CBD topicals?
The likelihood of a positive drug test result when using CBD topicals can be affected by factors such as product quality, labeling accuracy, and cross-contamination. It’s essential to consider these factors carefully to minimize the risk of a positive drug test.
What precautions can I take to ensure that I’m using CBD topicals safely with drug tests?
To use CBD topicals safely with drug tests, choose broad-spectrum or CBD isolate products, start with low doses, and discuss your CBD use with your employer. This can help ensure your safety and transparency in the workplace.
References
Zou, S., & Kumar, U. (2018). Cannabinoid Receptors and the Endocannabinoid System: Signaling and Function in the Central Nervous System. International journal of molecular sciences, 19(3), 833. https://doi.org/10.3390/ijms19030833
Sholler, D. J., Spindle, T. R., Cone, E. J., Goffi, E., Kuntz, D., Mitchell, J. M., Winecker, R. E., Bigelow, G. E., Flegel, R. R., & Vandrey, R. (2022). Urinary Pharmacokinetic Profile of Cannabidiol (CBD), Δ9-Tetrahydrocannabinol (THC) and Their Metabolites following Oral and Vaporized CBD and Vaporized CBD-Dominant Cannabis Administration. Journal of analytical toxicology, 46(5), 494–503. https://doi.org/10.1093/jat/bkab059
Hess, C., Krämer, M., & Madea, B. (2017). Topical application of THC containing products is not able to cause positive cannabinoid finding in blood or urine. Forensic science international, 272, 68–71. https://doi.org/10.1016/j.forsciint.2017.01.008

Written by Daniel Fayad - Subject Matter Expert and Website President
Dan Fayad is a results-driven healthcare administration expert and content writer. With a Master of Health Administration from the University of Southern California, he’s carved a niche for himself in the dynamic world of healthcare and business development. Dan uses his experience to educate and empower people on their wellness journeys.
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