Do CBD Creams Work for Pain Relief?
Written by: Daniel Fayad, Subject Matter Expert and Website President
Published: March 15, 2024; Last updated: April 6, 2024
- 1. Key Takeaways
- 2. Understanding CBD and Its Role in Topical Applications
- 3. The Analgesic Potential of CBD Creams
- 3.1 Determining CBD Potency and Efficacy
- 3.2 Comparing Topical CBD to Oral CBD
- 4. CBD Creams and Specific Pain Conditions
- 5. Decoding the Ingredients in CBD Topicals
- 6. How to Choose the Right CBD Products
- 7. Application Tips for Maximum Benefit
- 8. Legal Considerations and Understanding CBD Labels
- 9. Addressing Common Concerns and Myths
- 10. Clinical Insights and Healthcare Professional Opinions
- 11. Summary
- 12. Frequently Asked Questions
- 12.1 Can CBD be absorbed through the skin?
- 12.2 What does CBD cream do to your body?
- 12.3 What are the cons of CBD cream?
- 12.4 Does CBD cream stop chronic pain?
- 12.5 Does CBD balm work for pain?
- 13. References
In the realm of pain management, CBD creams have emerged as a promising and innovative alternative. Derived from the cannabis plant, these products have captured the attention of many individuals seeking a natural solution for chronic pain. But do they genuinely work? We’re here to unravel the truth and answer the question: do CBD creams work?
Key Takeaways
CBD creams are known for their potential pain-relieving properties, attributed to their interaction with the body’s endocannabinoid system. Still, their effectiveness varies based on factors like potency, dosage, and the presence of other natural ingredients.
Scientific research on CBD for pain management is still developing. However, some studies and anecdotal evidence suggest CBD creams may be effective for conditions such as arthritis, peripheral neuropathy, and jaw pain.
Choosing the suitable CBD cream involves evaluating factors like third-party lab testing and CBD type and considering the product’s potency and additional ingredients that can enhance its pain-relieving effects.
Understanding CBD and Its Role in Topical Applications

CBD, or Cannabidiol, is a cannabinoid compound extracted from the Cannabis Sativa plant. It doesn’t have the psychoactive properties of its counterpart THC and hence doesn’t induce a ‘high.’ Instead, it interacts with the body’s endocannabinoid system to regulate various bodily functions. ¹ This interaction extends to the skin, where CBD can handle a range of physiological processes, including:
Reducing inflammation
Balancing oil production
Moisturizing the skin
Soothing irritation
Promoting cell regeneration
CBD topicals, including creams and CBD lotions, are topical CBD products designed for direct skin application. They offer a localized approach to CBD, focusing its benefits on specific body areas. The substances in these products, such as CBD, penetrate the skin and permeate into the underlying layers through passive diffusion, providing targeted relief using a CBD topical.
CBD creams, in particular, have gained popularity as a CBD product for their potential to relieve chronic pain. By interacting with regional cannabinoid receptors on the skin, they offer a novel approach to pain management. They are especially beneficial in addressing peripheral nervous system disorders and various skin pathology conditions while not directly targeting the central nervous system.
The Analgesic Potential of CBD Creams
CBD creams have emerged as a potent tool in the sphere of pain relief owing to their analgesic properties. When applied to the skin, these products exert antinociceptive and anti-inflammatory effects on the peripheral nervous system, which in turn engage with pain receptors to provide relief. Yet, their effectiveness still needs to be fully understood, and much depends on factors such as potency, dosage, and product quality. ⁴
Although anecdotal evidence points towards CBD creams aiding in pain management, comprehensive scientific research is yet to reach maturity. Some of the most robust research involves CBD in combination with THC, but further investigation targeting the use of CBD for pain relief is necessary.
Determining CBD Potency and Efficacy
The potency of a CBD cream is determined by the concentration or strength of CBD in the product, which indicates the CBD content. This is a crucial factor when considering a CBD cream for pain relief. The potency of CBD creams and lotions varies widely. For instance, FABCBD CBD Body Salve comes in 1,000 and 3,000 mg of CBD per container, while Lazarus Naturals Fragrance-Free CBD Balm contains 3,000 mg in a 60-gram container.
The type of CBD used in the product also plays a significant role in determining its efficacy. The most common form of CBD used in skin creams is broad-spectrum CBD, which contains either no THC or only trace amounts. This type of CBD is popular due to its wide range of potential benefits. It’s often combined with other natural ingredients, such as tea tree oil, to enhance its effectiveness.
Comparing Topical CBD to Oral CBD
CBD for pain relief can be approached in two ways: through topical applications or oral administration. Each has its unique advantages and disadvantages. When administered to the skin, topical CBD does not enter the bloodstream, restricting its systemic impact. This makes it ideal for targeting specific skin pathologies or localized pain.
In contrast, oral CBD is absorbed into the bloodstream, delivering relief throughout the body, making it suitable for those seeking extensive systemic relief. However, it’s important to note that while topical CBD generally offers immediate, targeted relief, oral CBD may take longer to produce effects.
CBD Creams and Specific Pain Conditions
CBD creams have demonstrated potential in managing various pain conditions, including arthritis, peripheral neuropathy, and jaw pain. This is mainly due to their anti-inflammatory properties, which can help manage the inflammation associated with these conditions. ¹
For instance, individuals with arthritis have reported benefits such as decreased pain and enhanced sleep after using CBD creams. A study on rats in 2017 indicated that CBD might reduce joint inflammation and pain-related behaviors in osteoarthritis, suggesting its potential benefits for humans.
For peripheral neuropathy, randomized, double-masked, placebo-controlled trials have demonstrated the efficacy of topical CBD oil in alleviating symptoms and reducing pain. CBD cream may also alleviate jaw pain by targeting the inflammation and swelling within the affected area.
Decoding the Ingredients in CBD Topicals

Beyond CBD, other ingredients in CBD topicals can enhance their pain-relieving effects. These include pain-relieving agents like menthol, histamine dihydrochloride, lidocaine, arnica, aloe vera, emollients, and moisturizers.
Quality matters when it comes to these ingredients. Products incorporating ingredients from all-natural, U.S.-grown hemp, like FABCBD CBD Body Salve, suggest high quality and safety. They are often pesticide-free, non-GMO, and comply with stringent agricultural regulations, making them a superior choice.
Consumers must scrutinize product labels meticulously to spot known irritants or allergens. Selecting products with all-natural ingredients can help reduce the risk of contact dermatitis or allergic reactions.
How to Choose the Right CBD Products

Selecting the appropriate CBD cream involves thoughtful evaluation of numerous factors. One of these is third-party testing, which validates the product’s chemical properties, guaranteeing its safety, efficacy, and freedom from impurities.
When examining a Certificate of Analysis (COA) provided by third-party laboratories, users should ensure it aligns with the product description and that the laboratory has conducted contaminant testing, including screening for heavy metals, molds, and pesticides.
Another critical consideration is the type of CBD used in the cream. The product can contain one of three types of CBD: isolates, broad-spectrum, or full-spectrum.
The ingredients and potency of the product also play a significant role in ensuring the best results.
Application Tips for Maximum Benefit
The practical application of CBD creams can amplify their benefits. Integrating these products into a daily skincare routine, instead of sporadic application of larger quantities, can improve their efficacy.
However, users also need to exercise caution when applying CBD cream. Keeping the cream away from mucous membranes and broken skin is advisable to avoid potential irritation or adverse reactions.
Before using a CBD cream, it’s recommended to conduct a patch test by applying a small amount of the product to the inside of the wrist and observing for any signs of irritation. This can help prevent any potential allergic reactions.
Legal Considerations and Understanding CBD Labels

Understanding the legal facets and how to interpret CBD labels is crucial when buying CBD creams. Third-party testing is essential as it validates the potency, safety, and absence of harmful substances such as pesticides and heavy metals in the product.
CBD labeling requirements in the U.S. vary depending on whether the product is categorized as a drug or a dietary supplement. Consumers must be aware of these distinctions to ensure they purchase a compliant product.
One common concern is whether CBD creams can induce psychoactive effects similar to THC. However, CBD creams do not cause psychoactive effects as they typically contain minimal to no THC, the compound responsible for the euphoric effects associated with cannabis.
Addressing Common Concerns and Myths
Several common misconceptions about CBD creams necessitate clarification. Contrary to popular belief, CBD does not induce psychoactive effects similar to THC. While both are compounds present in the cannabis plant, CBD does not alter brain function, unlike THC.
Another myth is that CBD creams can be addictive. In reality, CBD creams pose no risk of addiction, providing a safer alternative for those who may be concerned about the addictive properties of other cannabis-derived products.
There’s also a misconception that CBD has not been scientifically proven to provide any health benefits or that CBD is a universal remedy. While CBD creams have shown potential in certain areas, these misconceptions lack support from scientific evidence.
Clinical Insights and Healthcare Professional Opinions
Insights from healthcare professionals and clinical studies provide valuable information about CBD creams’ potential benefits and limitations. It’s always advisable to seek advice from a healthcare professional before using CBD creams, especially if you have pre-existing conditions or are taking medications.
Clinical studies have indicated that CBD creams demonstrate the potential to provide pain relief, particularly in cases of arthritic pain, and in promoting wound healing. These findings underscore CBD creams’ potential benefits while emphasizing the necessity for further research.
While CBD is typically well tolerated, research suggests that high doses of CBD could be associated with indications of liver damage. Common side effects of using CBD creams may include fatigue, diarrhea, and alterations in appetite or weight.
Summary
This blog post has provided an in-depth exploration of CBD creams and their potential role in pain relief. We have explored the science behind CBD and its interaction with the body, the potential analgesic benefits of CBD creams, how to choose the right product, legal considerations, and user experiences.
While there is promising anecdotal evidence and some scientific research supporting the potential benefits of CBD creams for pain relief, it’s clear that more research is needed. As with any new product, it’s essential to consult with a healthcare professional before incorporating CBD creams into your pain management routine.
Frequently Asked Questions
Can CBD be absorbed through the skin?
Yes, CBD can be absorbed through the skin and efficiently reach the muscles and joint tissue within minutes.
What does CBD cream do to your body?
CBD cream may help alleviate the symptoms of some skin conditions and offer anti-inflammatory effects, potentially treating dry skin and certain inflammatory skin disorders. It may also help with painful joints.
What are the cons of CBD cream?
The main downside of CBD cream is the potential for skin irritation, which can manifest as itching, redness, or a rash. If you experience any discomfort or side effects, it’s essential to stop using the cream and seek advice from a healthcare professional.
Does CBD cream stop chronic pain?
Yes, CBD cream has been shown to calm arthritis pain and may be more effective than oral administration, but further research is needed to confirm its effectiveness for chronic pain.
Does CBD balm work for pain?
Yes, CBD balm may relieve aches and pains, especially related to arthritis. However, its effects are limited since most topical CBD products do not absorb into the bloodstream.
References
Zou, S., & Kumar, U. (2018). Cannabinoid Receptors and the Endocannabinoid System: Signaling and Function in the Central Nervous System. International journal of molecular sciences, 19(3), 833. https://doi.org/10.3390/ijms19030833
Makhakhe L. (2022). Topical cannabidiol (CBD) in skin pathology – A comprehensive review and prospects for new therapeutic opportunities. South African family practice : official journal of the South African Academy of Family Practice/Primary Care, 64(1), e1–e4. https://doi.org/10.4102/safp.v64i1.5493
Eskander, J. P., Spall, J., Spall, A., Shah, R. V., & Kaye, A. D. (2020). Cannabidiol (CBD) as a treatment of acute and chronic back pain: A case series and literature review. Journal of opioid management, 16(3), 215–218. https://doi.org/10.5055/jom.2020.0570
Weiner, S., By, Weiner, S., Writer, S. S., & 20, J. (2023, July 20). CBD: Does it work? is it safe? is it legal?. AAMC. https://www.aamc.org/news/cbd-does-it-work-it-safe-it-legal

Written by Daniel Fayad - Subject Matter Expert and Website President
Dan Fayad is a results-driven healthcare administration expert and content writer. With a Master of Health Administration from the University of Southern California, he’s carved a niche for himself in the dynamic world of healthcare and business development. Dan uses his experience to educate and empower people on their wellness journeys.
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